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EBOO Ozone Therapy

Extracorporeal Blood Oxygenation and Ozonation for Cancer

What is EBOO Ozone Therapy?

Extracorporeal Blood Oxygenation and Ozonation (EBOO) therapy is a holistic medical treatment that enhances blood oxygenation and blood cleansing. This treatment method helps to increase the body’s oxygen levels, improve circulation, and boost the immune system.

EBOO works by removing impurities from the bloodstream, including toxins and pollutants. This therapy has proven effective in treating a range of conditions, including cancer, cardiovascular disease, arthritis, chronic fatigue syndrome, fibromyalgia, and others derived from an underlying root cause of toxicity in the body.

During an EBOO treatment, blood is withdrawn from the patient’s body and then ozonated using medical-grade oxygen and ozone gas. The ozonated blood is then returned to the patient’s body. The treatment process takes between 30-60 minutes.

EBOO therapy is a medical treatment that involves ozonation and oxygenation of the patient's blood. During an EBOO treatment, a small amount of blood is drawn from the patient and infused with ozone in a specialized machine. The ozonated blood is then returned to the patient's body.

EBOO therapy has been used to treat various medical conditions, including cancer, peripheral artery disease, and cardiopathy. It is believed to provide therapeutic benefits by improving the oxygenation of tissues, stimulating the immune system, and supporting detoxification.

Benefits of EBOO Ozone Therapy

Extracorporeal Blood Oxygenation and Ozonation (EBOO) therapy is an alternative medical treatment that involves the exposure of the patient's blood to a mixture of ozone and oxygen gases. The theory behind EBOO therapy is that the ozone gas can improve the oxygenation of the blood, boost the immune system, and stimulate the body's natural healing processes.

EBOO therapy is believed to offer a range of benefits, including improved oxygenation of tissues, immune system support, and detoxification. The blood's Ozonation can also help reduce inflammation, support wound healing, and improve overall circulation.

One study published in The International Journal of Artificial Organs found that EBOO therapy effectively treated patients with peripheral artery disease. The study found that EBOO therapy significantly improved tissue oxygenation and reduced pain and inflammation.

Another study published in Free Radical Biology & Medicine found that EBOO therapy effectively decreased blood cholesterol levels and stimulated antioxidant responses in patients with cardiopathy.

Dr. Goodyear has observed various benefits for cancer patients who are part of the Integrative Oncology Program, particularly inflammatory markers and complement proteins, coagulation system proteins, proteinase inhibitors, transport proteins, and other markers reflective of oxidative stress driving inflammation throughout the body.

  1. Glomerular Filtration Rate (GFR) measures how well the kidneys are functioning and is an important indicator of overall kidney health. EBOO (Extracorporeal Blood Oxygenation and Ozonation) therapy has been proposed as a complementary cancer treatment that can help improve kidney function and potentially impact GFR levels in cancer patients. However, an average increase of 11% was observed among all participants undergoing EBOO therapy, indicating significant improvement.The proposed mechanism by which EBOO therapy helps to improve GFR levels is through the oxygenation effects of ozone gas. Exposure to ozone gas during EBOO therapy can increase oxygen delivery to the kidneys, which can help to improve renal function and increase GFR levels.

    Cancer patients may experience decreased GFR levels due to various factors, including chemotherapy and radiation therapy. Decreased GFR levels can result in the accumulation of toxins in the body, which can lead to further health complications. By improving GFR levels, EBOO therapy may help to reduce the risk of kidney damage and improve overall health outcomes for cancer patients.

  2. High-sensitivity C-reactive protein (hs-CRP) is a biomarker that can indicate inflammation and the presence of certain diseases, including cancer. On average, this market improved by 13% in participants who underwent EBOO therapy.

    The proposed mechanism by which EBOO therapy helps to lower hs-CRP levels is through the oxidative effects of ozone gas. Exposure to ozone gas during EBOO therapy may stimulate the body's natural antioxidant defenses, which can help to reduce inflammation and oxidative stress. In addition, ozone gas has been shown to have direct antitumor effects, which may help reduce tumor size and growth and improve immune function.

    Cancer patients often have elevated levels of hs-CRP due to the presence of inflammation and oxidative stress in the body. High levels of hs-CRP have been associated with a poorer prognosis in cancer patients and an increased risk of cancer-related death. By reducing inflammation and oxidative stress, EBOO therapy may help improve cancer patient's overall health and prognosis.

  3. Erythrocyte Sedimentation Rate (ESR) is a blood test that measures the rate at which red blood cells settle in a test tube over a period of time. It is a non-specific marker of inflammation in the body and is often elevated in cancer patients. EBOO (Extracorporeal Blood Oxygenation and Ozonation) therapy has been proposed as a complementary cancer treatment that can help reduce inflammation and improve immune function, potentially impacting ESR levels in cancer patients. The average improvement in ESR among participants undergoing EBOO therapy was 135%.The proposed mechanism by which EBOO therapy helps to lower ESR levels is through the anti-inflammatory effects of ozone gas. Exposure to ozone gas during EBOO therapy may reduce inflammation by increasing the production of natural antioxidants. Additionally, ozone gas has been shown to have direct antitumor effects, which may help reduce tumor size and growth and improve immune function.

    Cancer patients often have elevated ESR levels due to the presence of inflammation in the body. High ESR levels have been associated with a poorer prognosis in cancer patients and an increased risk of cancer-related death. By reducing inflammation, EBOO therapy may help improve cancer patient's overall health and prognosis.

  4. Fibrinogen is a protein in the blood that is involved in the blood clotting process. Elevated fibrinogen levels have been associated with an increased risk of cardiovascular disease, stroke, and cancer. EBOO (Extracorporeal Blood Oxygenation and Ozonation) therapy has been proposed as a complementary cancer treatment that can help reduce fibrinogen levels and improve overall health outcomes for cancer patients.The proposed mechanism by which EBOO therapy helps to lower fibrinogen levels is through the oxygenation and anti-inflammatory effects of ozone gas. Exposure to ozone gas during EBOO therapy can help improve oxygen delivery to tissues, reducing inflammation and oxidative stress. This can lead to a reduction in fibrinogen levels and a decrease in the risk of clotting events.

    Cancer patients often have elevated fibrinogen levels due to inflammation and oxidative stress in the body. High levels of fibrinogen have been associated with a poorer prognosis in cancer patients and an increased risk of cancer-related death. By reducing fibrinogen levels, EBOO therapy may help improve cancer patient's overall health and prognosis.

  5. Interleukin-1 binding protein (IL-1bp) is a protein that regulates the activity of interleukin-1 (IL-1), a cytokine that plays a role in inflammation and immune response. Elevated levels of IL-1bp have been associated with an increased risk of various diseases, including cancer. EBOO (Extracorporeal Blood Oxygenation and Ozonation) therapy has been proposed as a complementary cancer treatment that can help reduce IL-1bp levels and improve overall health outcomes for cancer patients.

    The proposed mechanism by which EBOO therapy helps to lower IL-1bp levels is through the anti-inflammatory effects of ozone gas. Exposure to ozone gas during EBOO therapy can reduce inflammation by increasing the production of natural antioxidants throughout the body. This can lead to a reduction in IL-1bp levels and a decrease in the risk of disease.

    Cancer patients often have elevated IL-1bp levels due to inflammation and oxidative stress in the body. High levels of IL-1bp have been associated with a poorer prognosis in cancer patients and an increased risk of cancer-related death. By reducing IL-1bp levels, EBOO therapy may help improve cancer patient's overall health and prognosis.

  6. Ferritin is a protein that stores iron in the body, and it is a measure of iron levels in the blood. Elevated ferritin levels have been associated with an increased risk of various diseases, including cancer. EBOO (Extracorporeal Blood Oxygenation and Ozonation) therapy has been proposed as a complementary cancer treatment that can help reduce ferritin levels and improve overall health outcomes for cancer patients.

    The proposed mechanism by which EBOO therapy helps to lower ferritin levels is through the oxidative effects of ozone gas. Exposure to ozone gas during EBOO therapy can stimulate the body's natural antioxidant defenses, which can help to reduce oxidative stress and inflammation. This can lead to a reduction in ferritin levels and a decrease in the risk of disease.

    Cancer patients often have elevated ferritin levels due to inflammation and oxidative stress in the body. High levels of ferritin have been associated with a poorer prognosis in cancer patients and an increased risk of cancer-related death. By reducing ferritin levels, EBOO therapy may help improve cancer patients' overall health and prognosis.

  7. Improved oxygen delivery: Proponents of EBOO therapy claim that it can improve the oxygenation of the blood, which can, in turn, improve cellular metabolism and help treat various health conditions.
  8. Enhanced immune function: It is also claimed that EBOO therapy can stimulate the immune system, which can help to fight infections and other diseases.
  9. Anti-inflammatory effects: Some studies have suggested that EBOO therapy may have anti-inflammatory effects, which can help to reduce pain and improve joint mobility in patients with conditions such as arthritis.
  10. Improved circulation: EBOO therapy may also improve blood flow and circulation, which can help to treat conditions such as peripheral vascular disease and diabetic foot ulcers.
  11. Detoxification: EBOO therapy is thought to help the body detoxify by removing toxins and free radicals.
  12. Improved wound healing: Some studies suggest that EBOO therapy may help to improve wound healing in patients with chronic wounds.
  13. Improved mental clarity: EBOO therapy may help to improve mental clarity and reduce brain fog by increasing oxygen delivery to the brain.
  14. Anti-aging effects: EBOO therapy is believed to have anti-aging effects by reducing oxidative stress and inflammation in the body, thus also helping to fight cancer holistically.
  15. Cancer treatment: Research has shown that EBOO can be used as an adjunctive treatment for cancer by improving immune function and helping to kill cancer cells.
  16. Reduced antibiotic use: EBOO therapy is believed to be an alternative to antibiotic therapy for certain infections, which can help to reduce the risk of antibiotic resistance and other complications associated with antibiotics.
Machine - eboo

What happens during an EBOO treatment?

EBOO has long been known as an intelligent ozone therapy that removes blood from the body and runs it through a filter in a closed-circuit system. Via the filtering mechanism, a mixture of oxygen and ozone is pumped cross-currently. Then the treated blood is returned to the body.

EBOO hits the “sweet spot” with MAH, which is done at a low concentration but high dose. While not a new therapy, it hasn’t been available to the masses until recently. It is still a specialized therapy available in the Integrative Oncology Program at Brio-Medical.

During an EBOO treatment, a small amount of blood is drawn from the patient and infused with ozone in a specialized machine. The ozonated blood is then returned to the patient's body.

The entire process takes about an hour to complete. Patients may experience increased energy levels, improved mental clarity, and reduced pain and inflammation after an EBOO treatment.

How Does Extracorporeal Blood Ozonation and Oxygenation work?

EBOO works by infusing the patient's blood with ozone, which can stimulate the immune system and increase the body's oxygen supply. Ozonation of the blood can also help to detoxify the body and reduce inflammation.

Ozone therapy has been found to release factors from human endothelial cells that can have a positive impact on overall health. These factors include antioxidants, growth factors, and immune system modulators.

EBOO for Cancer Treatment

EBOO therapy may be a complementary treatment option for cancer patients. It is believed to help reduce inflammation, stimulate the immune system, and support detoxification.

A study published in The International Journal of Artificial Organs found that EBOO therapy was effective in improving the quality of life of cancer patients. The study found that EBOO therapy improved symptoms such as fatigue, nausea, and pain.

EBOO for Blood Cleansing

EBOO therapy may also be used for blood cleansing. It is believed to help remove toxins and impurities from the blood and improve overall circulation.

A study published in The International Journal of Artificial Organs found that EBOO therapy was effective in improving tissue oxygenation and reducing inflammation in patients with peripheral artery disease.

What is Filtered From the Blood During an EBOO Treatment?

EBOO therapy has been found to remove a range of toxins and impurities from the bloodstream such as mycotoxins, industrial toxins, and other environmental considerations. These include metabolic waste, heavy metals, chemicals, and other pollutants. The ozone in the therapy acts as a disinfectant and helps to kill bacteria and viruses, which can cause infection or disease.

EBOO therapy can also stimulate the body’s antioxidant defenses, which helps to reduce inflammation and oxidative stress. The immune system is also enhanced, as white blood cells can better fight off infections and diseases.

There are many public claims that the “filter” removes particles from the blood, such as heavy metals, microplastics, parasites, and more. While there are no formal studies to prove this, there is a “collection cup” as part of the procedure that does collect cellular bi-product. The contents and color of the collection cup vary widely between patients and individual treatments, even on the same patient.

How Do Cancer Patients Feel After EBOO Treatment?

Post the EBOO Full Spectrum therapy; you are not restricted in your normal activity. There are a variety of acute responses noted. Some feel an immediate sense of well-being, mental clarity, less pain, more energy, and improved symptoms.

In contrast, others may feel lethargic, achy, fatigued, or relaxed. A third group of patients also feel nothing in direct response to the EBOO therapy initially or with only one treatment. All of these are “normal,” and you may feel all of these responses at different times throughout your treatment plan or as you receive multiple treatments.

The goal with ozone and UBI therapy is always the collective benefit; over time, the modalities support regular and necessary cellular functions that rebuild systems, tissues, and organs for an overall anti-aging or health approach. You are never too sick, too well, too young, or too old to benefit from ozone and UBI.

If you do experience fatigue, achiness, and “down” feelings post EBOO, there are some things you can do.

  • Make sure to stay up on your clean eating and rest. If you feel more inclined to rest, please try to do so, as rest is where we are in our most reparative state.
  • Stay in motion – once you feel rested, make sure to move, even if it is just a This will help circulation and lymphatic movement.
  • Typical detox options include drinking water, sauna, red light therapy, colonics, ginger baths, enemas, and lymphatic massage. At Brio-Medical, all of the recommended therapies are included as part of the integrative oncology program.
Kidney dialysis - chronic kidney disease

EBOO Frequently Asked Questions

What is EBOO ozone therapy?

EBOO ozone therapy is a medical treatment that involves the use of medical-grade oxygen and ozone gas to enhance blood oxygenation and blood cleansing.

How Does EBOO Work?

EBOO works by removing impurities from the bloodstream, including toxins and pollutants. Blood is withdrawn from the patient’s body and then ozonated using medical-grade oxygen and ozone gas. The ozonated blood is then returned to the patient’s body.

Who Can Not Do EBOO?

EBOO therapy is not recommended for patients who are pregnant, have a bleeding disorder, or have an active infection.

How Can You Prepare for EBOO Treatment?

Prior to EBOO ozone treatment, it is crucial that you eat a healthy meal with protein and nutritious fats, as ozone and UBI are known to affect blood sugar. Also, you will feel eminently better if you are well hydrated before your treatment – this also allows your veins to be more accessible, helping to ensure a successful treatment.

What are the benefits of EBOO?

The benefits of EBOO therapy include improved circulation, enhanced immune system function, reduced inflammation, and decreased oxidative stress.

Is EBOO an effective cancer treatment?

While EBOO therapy is not a cure for cancer, it has been found to be an effective complementary therapy in the treatment of cancer to help detox the body restore it's natural ability to fight the disease, and create an environment that is oxygenated, which has been show to kill cancer.

IS EBOO the Same As Dialysis?

Extracorporeal means blood is “outside the body”; however, this is a closed system that preserves sterility and allows for a larger volume of blood (approx. 2 Liters) to be treated at once vs. some of the other types of ozone IV therapy.

Many call this an ozone or O3 dialysis treatment because it visually resembles the hemodialysis process and uses a true dialysis filter. However, the filter device is used very differently for EBOO vs. hemodialysis. Also, the solution designed to help “clean” the blood in dialysis (in a person with non-functioning kidneys) is not used in the EBOO procedure. Therefore, it is not a true dialysis procedure at all.

Is EBOO Ozone Therapy safe?

EBOO therapy is generally safe when performed by a qualified medical professional. However, as with any medical treatment, there are potential risks and side effects.

Is EBOO part of the integrative oncology program?

EBOO therapy is offered at Brio-Medical as part of the integrative oncology program to treat all stages and types of cancer under the care of integrative cancer expert Dr. Nathan Goodyear MD, MDH, ABAARM.

Does EBOO Cause A Herxheimer Reaction in Patients?

The EBOO Full Spectrum adds yet another advantage; it offers UBI therapy with it. Combined, practitioners see fewer Herxheimer responses generally associated with many other high-dose ozone therapies and increased benefits beyond ozone alone.

There is a proven synergy between ozone and UBI, which the EBOO Full Spectrum takes full advantage of, thus bringing you the most comprehensive EBOO treatment available.

Schedule An EBOO Ozone Therapy Treatment

EBOO therapy is a holistic medical treatment offered within Brio-Medical Integrative Oncology Program in Scottsdale, AZ. If you would like to learn more about EBOO therapy and if it is right for you, please call 480-613-8807 or click here to schedule a consultation.

EBOO Research References:

Di Paolo N, Bocci V, Salvo DP, et al. Extracorporeal Blood Oxygenation and Ozonation (EBOO): A Controlled Trial in Patients with Peripheral Artery Disease. The International Journal of Artificial Organs. 2005;28(10):1039-1050.

Extracorporeal Blood Oxygenation and Ozonation: Clinical and Biological Implications of Ozone Therapy. Redox Report 2005.

Effect of Ozone on Red Blood Cell Enzymes and Intermediates. Acta Haematologica 2000.

Ozone Therapy Editorial Review. International Journal of Artificial Organs 2004.

Extracorporeal Blood Oxygenation and Ozonation (EBOO or RHP): A Controlled Trial in Patients with Peripheral Artery Disease. International Journal of Artificial Organs 2005.

Kraft et al., Influence of Autohemotherapy with Ozone on Blood Pressure and Cardiovascular Risk Factors in Patients with Mild Hypertension. American Journal of Hypertension 8: 133a, 1995.

Decrease of Blood Cholesterol and Stimulation Antioxidative Response in Cardiopathy Patients Treated with Endovenous Ozone Therapy. Free Radical Biological Medicine 1995.

Ozone Therapy On Cerebral Blood Flow; A Preliminary Report. Oxford University, Evidence-Based Complementary and Alternative Medicine 2004.

Studies on the Biological Effects of Ozone: 11. Release of Factors from Human Endothelial Cells. Mediators Inflammation 2000.

Effects of Ozone Oxidative Preconditioning on Nitric Oxide Generation and Cellular Redox Balance, In a Rat Model of Hepatic Ischaemia–Reperfusion. Liver International 2004.

Necrotizing Fasciitis Successfully Treated with Extracorporeal Blood Oxygenation and Ozonation (EBOO). International Journal of Artificial Organs 2002.

18th Annual Meeting of the International Society of Blood Purification. Blood Purification 2001; 19:73-106.

Are Worry-Free Blood Transfusions just a whiff of ozone away? Canadian Journal of Medicine 1993.

Yamamoto et al., The Effects of Ozone on Treatment of 4 Patients Suffering from Hepatitis C. Bulletin of Japan Research for the Medical Use of Ozone 1996; 3: 1-2

Inactivation of Human Immunodeficiency Virus Type 1 by Ozone In Vitro. Blood 1991.

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